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AHRQ
RECOMMENDATIONS
AIM TO IMPROVE
PATIENT SAFETY
ROCKVILLE, MDCould 11 fairly simple practices markedly improve your patients safety while in the hospital? A new federal report says yes.
Two years ago, in its alarming report on patient safety, the Institute of Medicine estimated that medical errors annually cause 44,000 to 98,000 deaths in US hospitals.[1] Since its release, many experts have debated the accuracy of its conclusions. But that reportand media coverage of individual fatalities due to medical errorsprompted a number of patient safety initiatives, including new evidence-based recommendations from the Agency for Healthcare Research and Quality (AHRQ).[2]
The recommendations address 79 patient safety practices identified through an extensive literature search. All 79 have at least some evidence that they can improve patient safety, related Nancy Foster, the AHRQs Coordinator for Quality Activities.
Rodney
A. Hayward, MD, endorses the recommendations. They
are just what we need to address quality improvement,
he told RESPIRATORY REVIEWS.
Dr. Hayward, a Professor of Health Management and Policy
at the University of Michigan in Ann Arbor, is one of the
authors of a recent study suggesting that the role of medical
errors in patient deaths has been exaggerated (see sidebar).
Nevertheless, he strongly supports the AHRQ report.
The AHRQ formulated its recommendations with help from the University of California at San FranciscoStanford University Evidence-Based Practice Center (EPC). The EPC reviewed the scientific literature for patient-safety data, focusing on inpatients for two reasons: Hospitalization is associated with significant risks, and the best data on improving safety relate to the hospital setting.
The EPC defined a patient safety practice as a type of process or structure whose application reduces the probability of adverse events resulting from exposure to the health care system across a range of diseases and procedures. This definition reflects current thinking that changing the health care system will be far more effective in reducing medical errors than will punishing individual providers, Ms. Foster said.
The 79 patient safety practices were rated on a 1-to-10 scale based on the strength of the evidence for their effectiveness and clinical judgment of their probable impact on adverse events. The EPC chose not to consider the difficulty or cost of implementation when rating each practice.
Eleven of the practices received especially high ratings. They are listed, in descending order, in Table 1.
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Table
1
Eleven Important
Strategies for Improving Patient Safety*
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1. Appropriate prophylaxis for venous thromboembolism
in at-risk patients.
2. Appropriate use of ß-blockers to prevent
perioperative morbidity and mortality.
3. Maximum sterile barrier use during central intravenous
catheter placement to prevent infections.
4. Appropriate antibiotic prophylaxis to prevent
perioperative infections.
5. Having patients recall and restate information
given them during the informed consent process.
6. Continuous aspiration of subglottic secretions
to prevent ventilator-associated pneumonia.
7. Pressure ulcer prevention with bedding material
that relieves pressure.
8. Central line insertion with real-time ultrasound
guidance to prevent complications.
9. Patient self-management of warfarin for appropriate
outpatient anticoagulation and prevention of complications.
10. Appropriate nutrition with particular emphasis
on early enteral nutrition for critically ill and
surgical patients.
11. Prevention of catheter-related infections with
antibiotic-impregnated central venous catheters.
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* Items are listed in descending order, with
the most highly rated items given first.
Data extracted from Evid Rep Technol Assess No
43. 2001.[2]
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This list
may be a good starting point for those who wish to get started
quickly on improving patient safety without analyzing the
entire 79-item list, Ms. Foster suggested. However,
we strongly encourage going back over the whole list to
identify the items that would be most beneficial for each
health care system, she told RESPIRATORY
REVIEWS.
FUTURE RESEARCH PRIORITIES
Because patient safety is a relatively new field, better evidence is needed to support many patient safety practices. According to the AHRQ, researchers should give 12 practices top priority. In addition to items 1, 4, and 10 on the list of 11 highly rated patient safety practices, these include:
Improved perioperative glucose control to decrease perioperative infections.
Localizing specific surgeries and procedures to high-volume centers.
Supplemental perioperative oxygen use to decrease perioperative infections.
Changes in nursing staff to decrease overall hospital morbidity and mortality.
Use of silver alloy-coated urinary catheters to prevent urinary tract infections.
Computerized physician-order entry with computerized decision support systems to decrease medication errors and adverse events.
Limiting antibiotic use in order to prevent hospital-acquired infections with resistant organisms.
Use of analgesics for acute abdominal pain without compromising the accuracy of diagnoses.
Improved hand-washing compliance through education and behavior change, sink technology and placement, and/or the use of antimicrobial washing products.
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Stats on Fatal Medical
Errors:
Eye-catching but Misleading
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ANN
ARBOR, MICHPhysicians should not
put much stock in the statistics on medical errorrelated
deaths that have gotten so much publicity. They are
probably unreliable, a new study suggests.[1] Hospitals
have been portrayed as dangerous places, and I think
that is the wrong portrayal, stated lead author
Rodney A. Hayward, MD.
Dr. Hayward and coauthor Timothy P. Hofer, MD, supervised
a retrospective review of 111 deaths at seven Veterans
Affairs medical centers from 1995 to 1996. The medical
records for these cases were evaluated by 14 board-certified
internists, who rated each death on a 1-to-5 scale
from definitely to definitely not
preventable with optimal care. They also estimated
the patients chances, had care been optimal,
of surviving to discharge and of living at least three
months post-discharge with good cognitive function.
Patients with hospital-acquired renal failure, hyperkalemia,
hyponatremia, or digoxin toxicity were intentionally
over-sampled because previous research has suggested
that patients with fluid and electrolyte imbalances
and drug toxicities have higher preventable death
rates. Terminally ill patients receiving end-of-life
comfort care were excluded.
Because many of the cases were evaluated multiple
times, 383 reviews were completed. As in previous
studies, nearly a quarter (22.7%) of the deaths
seemed to have at least some degree of preventability
with optimal care.
However, only 6% were rated as probably or definitely
preventable. In other words, just 6% of the patients
would have survived to discharge had care been optimal.
Furthermore, only 0.5% of the patients would
have lived at least three months with good cognitive
function after discharge, the reviewers estimated.
Timothy Begany
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Reference
1. Hayward RA, Hofer TP. Estimating
hospital deaths due to medical errors: preventability
is in the eye of the reviewer. JAMA. 2001;286:415-420.
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Timothy Begany
References
1. Kohn LT, Corrigan JM, Donaldson MS, eds. To Err Is Human:
Building a Safer Health System. Washington, DC: National
Academy Press; 2000.
2. Evidence Report/Technology Assessment Number 43: Making
Health Care Safer: A Critical Analysis of Patient Safety Practices.
Rockville, Md: US Dept of Health and Human Services, Agency
for Healthcare Research and Quality; 2001. AHRQ publication
01-E058.
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